Never Let Me Go by Kazuo Ishiguro
(Recommended by yilun / rng)
Ishiguro's contribution to the real technical debate (this is vague because I don't like spoilers) is minimal, a mere gloss that promptly discredits the 'science' from “science fiction”.
Yet, nothing is more heartbreaking than his understated treatment of what the novel is really about - the steady erosion of hope.
It's about repressing what we all know: in this life people fail one another, grow old and fall to pieces. It's about knowing that while you must keep calm, keeping calm won't change a thing.
Never Let Me Go makes me want to do anything to convince myself that I’m more alive, more conscious, more powerful than any of those characters. And, in the end, the frighteningly clever novel isn't about the science of anything at all.
M Harrison says:
"It's about why we don't explode, why we don't just wake up one day and go screaming down the street, kicking everything to pieces out of the infuriating, completely personal sense of our lives never having been what they could have been."